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Coronary artery spasm 2, susceptibility to

MedGen UID:
461056
•Concept ID:
C3149706
•
Finding
Synonym: CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO
 
OMIM®: 168820

Professional guidelines

PubMed

The role of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 genotypes in alcohol-induced vasospastic angina.
Seki T, Okayama H, Isoyama S, Kagaya Y, Shirato K, Munakata K, Kanazawa M, Tamaki K, Hiramoto T, Okayama M, Kasahara S
Tohoku J Exp Med 1999 Apr;187(4):311-22. doi: 10.1620/tjem.187.311. PMID: 10503603

Recent clinical studies

Etiology

RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction.
Hikino K, Koyama S, Ito K, Koike Y, Koido M, Matsumura T, Kurosawa R, Tomizuka K, Ito S, Liu X, Ishikawa Y, Momozawa Y, Morisaki T, Kamatani Y, Mushiroda T, Terao C; Biobank Japan Project
JAMA Cardiol 2024 Aug 1;9(8):723-731. doi: 10.1001/jamacardio.2024.1483. PMID: 38888930Free PMC Article
Familial risk of vasospastic angina: a nationwide family study in Sweden.
Ricci F, Banihashemi B, Pirouzifard M, Sundquist J, Sundquist K, Sutton R, Fedorowski A, Zoller B
Open Heart 2023 Dec 6;10(2) doi: 10.1136/openhrt-2023-002504. PMID: 38056914Free PMC Article
The effect of vasodilatory medications on radial artery spasm in patients undergoing transradial coronary artery procedures: a systematic review.
Curtis E, Fernandez R, Lee A
JBI Database System Rev Implement Rep 2017 Jul;15(7):1952-1967. doi: 10.11124/JBISRIR-2016-003039. PMID: 28708754
Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST-Segment Elevation Myocardial Infarction.
Mizuno Y, Hokimoto S, Harada E, Kinoshita K, Nakagawa K, Yoshimura M, Ogawa H, Yasue H
J Am Heart Assoc 2016 May 6;5(5) doi: 10.1161/JAHA.116.003247. PMID: 27153870Free PMC Article
Coronary spasm and acute myocardial infarction due to a mutation (V734I) in the nucleotide binding domain 1 of ABCC9.
Smith KJ, Chadburn AJ, Adomaviciene A, Minoretti P, Vignali L, Emanuele E, Tammaro P
Int J Cardiol 2013 Oct 9;168(4):3506-13. Epub 2013 Jun 3 doi: 10.1016/j.ijcard.2013.04.210. PMID: 23739550

Diagnosis

Familial risk of vasospastic angina: a nationwide family study in Sweden.
Ricci F, Banihashemi B, Pirouzifard M, Sundquist J, Sundquist K, Sutton R, Fedorowski A, Zoller B
Open Heart 2023 Dec 6;10(2) doi: 10.1136/openhrt-2023-002504. PMID: 38056914Free PMC Article
Acute ST Elevation Myocardial Infarction Due to Allergic Reaction, Kounis Syndrome.
Rajha E, Didi A, Dakik H, Mufarrij A
Am J Emerg Med 2020 Feb;38(2):409.e5-409.e7. Epub 2019 Nov 16 doi: 10.1016/j.ajem.2019.10.006. PMID: 31785976
Masked inherited primary arrhythmia syndromes in sudden cardiac death patients accompanied by coronary vasospasm.
Lee KH, Park HW, Eun JN, Cho JG, Yoon NS, Kim MR, Ku YH, Park H, Lee SH, Kim JH, Kim MC, Kim WJ, Kim HK, Cho JY, Park KH, Sim DS, Yoon HJ, Kim KH, Hong YJ, Kim JH, Ahn Y, Jeong MH, Park JC
Korean J Intern Med 2017 Sep;32(5):836-846. Epub 2017 Aug 11 doi: 10.3904/kjim.2015.283. PMID: 28797161Free PMC Article
Coronary spasm and acute myocardial infarction due to a mutation (V734I) in the nucleotide binding domain 1 of ABCC9.
Smith KJ, Chadburn AJ, Adomaviciene A, Minoretti P, Vignali L, Emanuele E, Tammaro P
Int J Cardiol 2013 Oct 9;168(4):3506-13. Epub 2013 Jun 3 doi: 10.1016/j.ijcard.2013.04.210. PMID: 23739550
Identification of genetic factors and development of genetic risk diagnosis systems for cardiovascular diseases and stroke.
Yamada Y
Circ J 2006 Oct;70(10):1240-8. doi: 10.1253/circj.70.1240. PMID: 16998253

Therapy

Acute ST Elevation Myocardial Infarction Due to Allergic Reaction, Kounis Syndrome.
Rajha E, Didi A, Dakik H, Mufarrij A
Am J Emerg Med 2020 Feb;38(2):409.e5-409.e7. Epub 2019 Nov 16 doi: 10.1016/j.ajem.2019.10.006. PMID: 31785976
The effect of vasodilatory medications on radial artery spasm in patients undergoing transradial coronary artery procedures: a systematic review.
Curtis E, Fernandez R, Lee A
JBI Database System Rev Implement Rep 2017 Jul;15(7):1952-1967. doi: 10.11124/JBISRIR-2016-003039. PMID: 28708754
Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST-Segment Elevation Myocardial Infarction.
Mizuno Y, Hokimoto S, Harada E, Kinoshita K, Nakagawa K, Yoshimura M, Ogawa H, Yasue H
J Am Heart Assoc 2016 May 6;5(5) doi: 10.1161/JAHA.116.003247. PMID: 27153870Free PMC Article
Potent vasodilatory effect of fasudil on radial artery graft in coronary artery bypass operations.
Watanabe G, Yamaguchi S, Takagi T, Tomita S, Tuan PM
Ann Thorac Surg 2014 Mar;97(3):845-50. Epub 2013 Nov 26 doi: 10.1016/j.athoracsur.2013.10.027. PMID: 24286636
Mutation of ARHGAP9 in patients with coronary spastic angina.
Takefuji M, Asano H, Mori K, Amano M, Kato K, Watanabe T, Morita Y, Katsumi A, Itoh T, Takenawa T, Hirashiki A, Izawa H, Nagata K, Hirayama H, Takatsu F, Naoe T, Yokota M, Kaibuchi K
J Hum Genet 2010 Jan;55(1):42-9. Epub 2009 Nov 13 doi: 10.1038/jhg.2009.120. PMID: 19911011

Prognosis

RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction.
Hikino K, Koyama S, Ito K, Koike Y, Koido M, Matsumura T, Kurosawa R, Tomizuka K, Ito S, Liu X, Ishikawa Y, Momozawa Y, Morisaki T, Kamatani Y, Mushiroda T, Terao C; Biobank Japan Project
JAMA Cardiol 2024 Aug 1;9(8):723-731. doi: 10.1001/jamacardio.2024.1483. PMID: 38888930Free PMC Article
Masked inherited primary arrhythmia syndromes in sudden cardiac death patients accompanied by coronary vasospasm.
Lee KH, Park HW, Eun JN, Cho JG, Yoon NS, Kim MR, Ku YH, Park H, Lee SH, Kim JH, Kim MC, Kim WJ, Kim HK, Cho JY, Park KH, Sim DS, Yoon HJ, Kim KH, Hong YJ, Kim JH, Ahn Y, Jeong MH, Park JC
Korean J Intern Med 2017 Sep;32(5):836-846. Epub 2017 Aug 11 doi: 10.3904/kjim.2015.283. PMID: 28797161Free PMC Article
The effect of vasodilatory medications on radial artery spasm in patients undergoing transradial coronary artery procedures: a systematic review.
Curtis E, Fernandez R, Lee A
JBI Database System Rev Implement Rep 2017 Jul;15(7):1952-1967. doi: 10.11124/JBISRIR-2016-003039. PMID: 28708754
Low density lipoprotein particles are small in patients with coronary vasospasm.
Miwa K
Int J Cardiol 2003 Feb;87(2-3):193-201. doi: 10.1016/s0167-5273(02)00250-4. PMID: 12559540
A psychobehavioral factor, alexithymia, is related to coronary spasm.
Numata Y, Ogata Y, Oike Y, Matsumura T, Shimada K
Jpn Circ J 1998 Jun;62(6):409-13. doi: 10.1253/jcj.62.409. PMID: 9652315

Clinical prediction guides

RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction.
Hikino K, Koyama S, Ito K, Koike Y, Koido M, Matsumura T, Kurosawa R, Tomizuka K, Ito S, Liu X, Ishikawa Y, Momozawa Y, Morisaki T, Kamatani Y, Mushiroda T, Terao C; Biobank Japan Project
JAMA Cardiol 2024 Aug 1;9(8):723-731. doi: 10.1001/jamacardio.2024.1483. PMID: 38888930Free PMC Article
Familial risk of vasospastic angina: a nationwide family study in Sweden.
Ricci F, Banihashemi B, Pirouzifard M, Sundquist J, Sundquist K, Sutton R, Fedorowski A, Zoller B
Open Heart 2023 Dec 6;10(2) doi: 10.1136/openhrt-2023-002504. PMID: 38056914Free PMC Article
High susceptibility of atherosclerotic coronary arteries to the onset of vasospasm and angina pectoris-like symptoms due to coronary spasm in WHHLMI rabbits.
Koike T, Tamura S, Yu Y, Kuniyoshi N, Shiomi M
Exp Anim 2016 Nov 1;65(4):419-426. Epub 2016 Jun 14 doi: 10.1538/expanim.16-0035. PMID: 27301847Free PMC Article
Mutation of ARHGAP9 in patients with coronary spastic angina.
Takefuji M, Asano H, Mori K, Amano M, Kato K, Watanabe T, Morita Y, Katsumi A, Itoh T, Takenawa T, Hirashiki A, Izawa H, Nagata K, Hirayama H, Takatsu F, Naoe T, Yokota M, Kaibuchi K
J Hum Genet 2010 Jan;55(1):42-9. Epub 2009 Nov 13 doi: 10.1038/jhg.2009.120. PMID: 19911011
Human saphenous vein and coronary bypass surgery: ultrastructural aspects of conventional and "no-touch" vein graft preparations.
Ahmed SR, Johansson BL, Karlsson MG, Souza DS, Dashwood MR, Loesch A
Histol Histopathol 2004 Apr;19(2):421-33. doi: 10.14670/HH-19.421. PMID: 15024703

Recent systematic reviews

The effect of vasodilatory medications on radial artery spasm in patients undergoing transradial coronary artery procedures: a systematic review.
Curtis E, Fernandez R, Lee A
JBI Database System Rev Implement Rep 2017 Jul;15(7):1952-1967. doi: 10.11124/JBISRIR-2016-003039. PMID: 28708754

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